当前位置: 首页 > 新闻聚焦 > 正文

【生物医学工程高精尖中心】法国索邦大学Pascal LAUGIER教授学术报告通知

发布时间:2018-10-29 20:47   点击次数:

法国索邦大学Pascal LAUGIER教授学术报告通知

 

 

报告题目:Opportunities in translating resonant ultrasound spectroscopy into bone applications

 

时间: 2018年10月31日(周三)下午2:30

 

地点:逸夫楼317学术报告厅

 

报告人:Pascal LAUGIER教授

 


报告摘要:

 

Bone mechanical properties which fascinates not only scientists but also engineers are the results of      the highly hierarchized and organized structure and the compositional properties spanning over several  lengths from the nanoscale to the macroscale. Deep understanding of parameters affecting bone mechanical  behavior is necessary to better predict and treat bone diseases, improve orthopedic implants design, and engineer bio-inspired materials. Resonant ultrasound spectroscopy is a powerful method to investigate  bone stiffness at different scales. In this work, a special focus is placed on human cortical bone elastic   properties both at the millimeter and micrometer scales.

 

Based on a multimodal approach (resonant ultrasound spectroscopy, synchrotron radiation micro-computed tomography, Fourier transform infrared micro-spectroscopy and biochemistry experiments), our results provide strong evidence that intra-cortical porosity and degree of mineralization are the most    important determinants of bone stiffness at millimeter scale in an elderly population. Microstructural     characteristics independent of porosity have non-measurable effects on bone stiffness at this level. At the micrometer scale, a novel inverse homogenization approach is introduced which can evaluate bone matrix anisotropic elastic properties with a good accuracy for all the stiffness constants.

 

 

 

  

报告人简介:

Pascal LAUGIER教授担任法国索邦大学(由原巴黎六大 和 原巴黎四大 合并)教授、法国国家科研中心(CNRS)一级研究员,巴黎六大医学成像实验室主任(LIP)。他曾获1993年度法国CNRS的铜质勋章,1998年度法国物理学会Yves Rocard奖,2001年度欧洲重大创新奖,2009年度法国声学学会勋章。他先后当选为欧洲科学院院士,美国医学生物工程学会(AIMBE)Fellow、美国声学学会(ASA)Fellow、美国超声医学学会荣誉Fellow、美国骨矿物质研究学会会员、欧洲生物力学学会会员。现任《IEEE Trans on UFFC》副主编,以及包括《Ultrasound in Medicine and Biology》与《Ultrasonic Imaging》在内的多个期刊编委。

研究主要集中在医学成像与生物医学超声方面,尤其是在骨定量超声测量方面有着很深的学术造诣,他的研究小组曾成功研制了欧洲第一台骨密度检测仪与骨成像仪,是该领域的著名学者,有着非常高的知名度。迄今为止,Pascal教授总共发表期刊论文近200篇,国际会议论文320篇,会议摘要700余篇,发明专利12个,发表专著与章节共25章,曾任15个国际会议的主席与副主席。