贺子龙 医工百人/副研究员/博士生导师
医工交叉创新研究院/大数据精准医疗高精尖创新中心
北航教师个人主页：http://shi.buaa.edu.cn/koheallen0828/zh_CN/index.htm
电子邮箱：hezilong@buaa.edu.cn
【教育背景】
2011.09-2016.07 中国科学院北京基因组研究所 | 生物信息学 | 博士学位
【工作经历】
2016.09-2020.04中国科学院微生物研究所 | 微生物组学 | 博士后
2020.04-至今 北京航空航天大学 | 医工交叉创新研究院 | 副研究员
【研究领域】
1）基于宏基因组学等多组学手段研究人体微生物与疾病的关系；
2）病原菌耐药组以及泛基因组研究；
3）基于医学大数据的整合以及分子标记筛选等。
【代表性科研项目】
主持中国博士后面上基金项目，并参与多项国家级科研项目
【代表性论著】
目前已发表文章16篇，其中SCI期刊15篇（第一作者文章7篇）。
第一作者文章
#代表并列第一作者
1. Zilong He, Huangkai Zhang, Shenghan Gao, Martin J. Lercher, Wei-Hua Chen*, Songnian Hu*, Evolview v2: an online visualization and management tool for customized and annotated
phylogenetic trees. Nucleic Acids Research 2016 （Q1, IF:9.202）
2. Zilong He#, Chengwei Zhang#, Wanfei Liu#, Qiang Lin, Ting Wei, Hasan AwadAljohi*, Wei-hua Chen*, Songnian Hu*, DRDB: An online date palm genomic resource database. Frontiers in plant science 2017 （Q1, IF:4.298）
3. Yao Zhai#, Zilong He#, Yu Kang, Haiying Yu, Jianfeng Wang, Pengcheng Du, Zhao Zhang, Songnian Hu*,
Zhancheng Gao*, Complete nucleotide sequence of pH11, an IncHI2 plasmid conferring multi-antibiotic resistance and multi-heavy metal resistance genes in a clinical Klebsiella pneumoniae isolate. Plasmid 2016 （Q3, IF:1.732）
4. Le Xue#, Zilong He#, Xiaochun Bi, Wei Xu, Ting Wei, Shuangxiu Wu*, Songnian Hu*. Transcriptomic profiling reveals
MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng. BMC genomics 2019 (Q1, IF:3.501)
5. Na L. Gao#, Zilong He#, Qianhui Zhu#, Puzi Jiang, Songnian Hu*, Wei-Hua Chen*, Selection for Cheaper Amino Acids Drives Nucleotide Usage at Translation Start in Eukaryotic Genes,
Genomics, Proteomics & Bioinformatics 2019 (accepted).（Q1, IF:6.615）
6. Jing Zhang#, Zilong He#, JinTian Xu#, Shuting Song#, Qianhui Zhu, Guoguo Wu, Ying Guan, Xiaonong Wu,
Rong Yue, Yue Wang, Tao Yu, Songnian Hu, Fuping Lu, Huitu Zhang, Semi-rational mutagenesis of an industrial Streptomyces fungicidicus strain for improved enduracidin productivity,
Applied Microbiology and Biotechnology 2020. （Q1, IF:3.53）
7. Yu Kang#, Lina Yuan#, Xing Shi#, Yanan Chu#, Zilong He#, Xinmiao Jia, Qiang Lin, Qin Ma, Jian Wang, Jingfa Xiao,
Songnian Hu, Zhancheng Gao, Fei Chen and Jun Yu. A fine-scale map of genome-wide recombination in divergent Escherichia coli population, Briefings in Bioinformatics.2020 （Q1, IF:8.99）
参与作者文章
8. Chaorong Tang#, Meng Yang#, Yongjun Fang#, Yingfeng Luo#, Shenghan Gao, Xiaohu Xiao, Zewei An, Binhui Zhou,
Bing Zhang, Xinyu Tan, Hoong-Yeet Yeang, Yunxia Qin, Jianghua Yang, Qiang Lin, Hailiang Mei, Pascal Montoro, Xiangyu Long, Jiyan Qi, Yuwei Hua,
Zilong He, Min Sun, Wenjie Li, Xia Zeng, Han Cheng, Ying Liu, Jin Yang, Weimin Tian, Nansheng Zhuang, Rizhong Zeng,
Dejun Li, Peng He, Zhe Li, Zhi Zou, Shuangli Li, Chenji Li, Jixiang Wang, Dong Wei, Chao-Qiang Lai, Wei Luo, Jun Yu*, Songnian Hu* & Huasun Huang*, The rubber tree genome reveals new insights into rubber
production and species adaptation. Nature Plant 2016 （Q1, IF:10.3）
9. Shuai Wang#, Sen Wang#, Yingfeng Luo, Lihua Xiao, Xuenong Luo, Shenghan Gao, Yongxi Dou, Huangkai Zhang,
Aijiang Guo, Qingshu Meng, Junling Hou, Bing Zhang, Shaohua Zhang, Meng Yang, Xuelian Meng, Hailiang Mei, Hui Li,
Zilong He, Xueliang Zhu, Xinyu Tan, Xing-quan Zhu, Jun Yu, Jianping Cai, Guan Zhu, Songnian Hu* & Xuepeng Cai*,
Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host.
Nature Communication 2016 （Q1, IF:11.329）
10. Ting Wei, Zilong He, XinYu Tan, Xue Liu, XiaoYuan, Yingfeng Luo*, Songnian Hu*, An integrated RNA-Seq and network study reveals a complex regulation process of rice embryo during seed germination. Biochemical and
Biophysical Research Communications 2015 （Q2, IF:2.466）
11. Yatao Guo, Yao Zhai, Zhao Zhang, Daixi Li, Zhanwei Wang, Jingquan Li, Zilong He, Songnian Hu, Yu Kang* and
Zhancheng Gao*, Complete Genomic Analysis of a Kingdom-Crossing Klebsiella variicola Isolate. Frontiers in microbiology 2018 （Q1, IF:4.019）
12. Chaoran Dong#, Jiemei Chen#, Jilin Zheng#, Yiming Liang#, Tao Yu#, Yupeng Liu, Feng Gao, Jie Long, Hangyu Chen,
Qianhui Zhu, Zilong He, Songnian Hu, Chuan He, Jian Lin*, Yida Tang*, Haibo Zhu*, 5-Hydroxymethylcytosine signatures
in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease. Clinical Epigenetics 2020 （Q1, IF:5.028）
13. Dai-Xi Li, Yao Zhai, Zhao Zhang, Ya-Tao Guo, Zhan-Wei Wang, Zi-Long He, Song-Nian Hu, Yu-Sheng Chen, Yu Kang, Zhan-Cheng Gao, Genetic factors related to the widespread dissemination of ST11 extensively drug-resistant carbapenemase-producing Klebsiella pneumoniae strains within hospital. Chin Med J (Engl). 2020 （Q1, IF:1.585）
14. Yao Zhai, Daixi Li, Pengcheng Du, Zhao Zhang, Zilong He, Yatao Guo, Yusheng Chen, Yu Kang, Songnian Hu,
Zhancheng Gao, Complete sequences of two new KPC-harboring plasmids in Klebsiella pneumoniae ST11 strains in China.
J Glob Antimicrob Resist 2020 (Q2, IF:2.706)
15. Guo Guangxin, Kexin Li, Qianhui Zhu, Chunyan Zhao, Chao Li, Shun Zhou, Zilong He, Songnian Hu, Bin Xia, Yichao Ren，Improvements of immune genes and gut microbial composition of juvenile turbot (Scophthalmus maximus) with dietary
oregano oil and probiotics. Aquaculture 2021 (Q1,IF: 4.242)
16. 《宏基因组测序病原微生物监测生物信息学分析规范化管理专家共识》，中华检验医学杂志, 2021年9月44卷第9期 ，鲁辛辛，胡松年，王玫，贺子龙，杨继勇，谷丽，隋文君
