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王迪

发布时间:2021-10-14 11:38   点击次数:

王迪 助理教授/硕士生导师

北京航空航天大学/医学科学与工程学院

电子邮箱:wangdi09@126.com

教师主页:https://shi.buaa.edu.cn/wangdi/zh_CN/index.htm

欢迎生物医学工程(医电方向)、基础医学、计算机、医学信息学等专业感兴趣的考生邮件联系。

 

【主要研究领域】

脑电生理;癫痫;脑功能;认知神经科学;神经调控

 

【研究方向简介】

担任国际抗癫痫联盟青年组委员、北京神经科学学会脑功能疾病与认知发育专业委员会委员等,参与国际抗癫痫联盟导师-学员项目。聚焦于运用颅内电生理手段研究神经机制,重视前沿研究方法和工具的学习与综合运用,注重于临床与工科的结合以及临床应用转化研究,研究内容主要包括以下五方面:

[1] 将工程中的信号检测与分析技术直接融入癫痫临床诊疗,研究准确定位癫痫源的新技术和方法;

[2] 通过颅内多尺度脑电生理记录和包括电生理和影像在内的多模态技术,研究癫痫的发生传播和终止的时空特征;

[3] 研究神经调控治疗难治性癫痫的电生理效应和机制完善国际治疗癫痫发作的理论体系,进一步带来临床治疗战略的改变;

[4] 通过包括头皮和颅内多尺度脑电生理记录和包括电生理和影像在内的多模态技术,研究情感、记忆等认知功能的加工处理过程和网络连接;

[5] 通过包括头皮和颅内多尺度脑电生理记录和包括电生理和影像在内的多模态技术,研究睡眠的电生理机制等。

 

【教育背景】

2017-92020-7, 首都医科大学神经病学博士导师王玉平 教授,任连坤 教授

2009-92017-7, 首都医科大学神经病学本硕连读导师王玉平 教授,任连坤 教授

 

【工作经历】

2020-10至今北京航空航天大学医学科学与工程学院助理教授

 

【主持或参加科研项目】

1. 首都医科大学宣武医院,横向科研项目,SEEG引导的立体交叉毁损微创治疗颞叶癫痫的基础与临床研究,2023-09 2024-08

2. 首都医科大学宣武医院,横向科研项目,激光消融量效关系及安全性验证,2023-09 2024-08

3. 北京航空航天大学医工卓越创新计划,不同模式直接电刺激治疗人类药物难治性癫痫的网络调控机制,2021-092023-09

4. 国家自然科学基金委员会,面上项目,丘脑底核电刺激调控治疗药物难治性运动皮质癫痫的网络机制研究,2021-012024-12

5. 北京市自然科学基金委员会,面上项目,情感性癫痫发作症状功能解剖网络构建与跨频率耦合电生理机制研究,2021-012022-12

6. 国家自然科学基金委员会,面上项目,基于颅内脑电的人类恐惧记忆注意偏向神经机制研究,2018-012021-12

7. 国家自然科学基金委员会,青年科学基金项目,心因性非痫性发作额顶功能的脑磁电生理研究,2016-012018-12

 

【代表论文】

1. Di Wang#*, Di Lu#, Mingtai Zhang Anqi Dai, Guangyuan Jin, Qiao Wang, Yuyang Zhang, Philippe Kahane. Advances in epileptic network findings of hypothalamic hamartomas. J Cent Nerv Syst Dis, 2024.

2. Huaqiang Zhang#, Di Wang#, Penghu Wei, Xiaotong Fan, Yanfeng Yang, Yang An, Yang Dai, Tao Feng, Yongzhi Shan, Liankun Ren*, Guoguang Zhao*. Integrative roles of human amygdala subdivisions: Insight from direct intracerebral stimulations via stereotactic EEG. Hum Brain Mapp, 2023, 44(9): 3610-3623.

3. Lei Qi#,, Cuiping Xu#,, Xueyuan Wang, Jialin Du, Quansheng He, Di Wu, Xiaopeng Wang, Guangyuan Jin, Qiao Wang, Jia Chen, Di Wang, Huaqiang Zhang, Xiaohua Zhang, Penghu Wei, Yongzhi Shan, Zaixu Cui, Yuping Wang, Yousheng Shu, Guoguang Zhao*, Tao Yu*, Liankun Ren*. Intracranial direct electrical mapping reveals the functional architecture of the human basal ganglia. Commun Biol, 2022, 5(1): 1123.

4. Huaqiang Zhang, Di Wang, Penghu Wei, Xiaotong Fan, Liankun Ren, Yongzhi Shan*, Guoguang Zhao*. Successful stereoelectroencephalography-guided radiofrequency thermocoagulation in the treatment of a patient with mesial frontal region-originated mirthful gelastic seizure. Clin Neurol Neurosurg, 2021, 207: 106713.

5. Liankun Ren#*, Tao Yu#*, Di Wang#, Xueyuan Wang, Duanyu Ni, Guojun Zhang, Fabrice Bartolomei, Yuping Wang, Yongjie Li*. Subthalamic nucleus stimulation modulates motor epileptic activity in humans. Annals of Neurology, 2020, 88(2): 283-296.

6. Di Wang#, Yongzhi Shan#, Fabrice Bartolomei, Philippe Kahane, Yang An, Muyang Li, Huaqiang Zhang, Xiaotong Fan, Siqi Ou, Yanfeng Yan, Penghu Wei, Chao Lu, Yihe Wang, Jialin Du, Liankun Ren*, Yuping Wang*, Guoguang Zhao*. Electrophysiological properties and seizure networks in hypothalamic hamartoma. Annals of Clinical and Translational Neurology, 2020, 7(5): 653-666.

7. Minjing Hu#, Di Wang#, Xuanxiu Ji#, Tao Yu, Yongzhi Shan, Xiaotong Fan, Jialin Du, Xiaohua Zhang, Guoguang Zhao*, Yuping Wang*, Liankun Ren*, Liégeois-Chauvel Catherine. Neural processes of auditory perception in Heschl's gyrus for upcoming acoustic stimuli in humans. Hearing Research, 2020, 388: 107895.

8. Di Wang, Zhaoyang Huang, Liankun Ren, Jing Liu, Xueyuan Wang, Tao Yu, Minjing Hu, Xueming Wang, Jialin Du, Duanyu Ni, Xi Zhang, Runshi Gao, Liang Qiao, Yuping Wang*. Amygdalar and hippocampal beta rhythm synchrony during human fear memory retrieval. Acta Neurochirurgica, 2020, 162(10): 2499-2507.

9. Di Wang#, Penghu Wei#, Yongzhi Shan#, LianKun Ren*, Yuping Wang*, Guoguang Zhao*. Optimized stereoelectroencephalography-guided radiofrequency thermocoagulation in the treatment of patients with focal epilepsy. Annals of Translational Medicine, 2020, 8(1): 15.

10. Jing Liu#, Hui Zhang#, Tao Yu, Duanyu Ni, Liankun Ren, Qinhao Yang, Baoqing Lu, Di Wang, Rebekka Heinen, Nikolai Axmacher, Gui Xue*. Stable maintenance of multiplerepresentational formats in human visual short-term memory. Proceedings of the National Academy of Sciences, 2020, 117(51): 32329-32339.

11. Xueyuan Wang#, Jialin Du#, Di Wang#, Cuiping Xu, Zhiwei Ren, Yuping Wang, Yongjie Li, Tao Yu*, Liankun Ren*. Long-term outcome of unilateral deep brain stimulation of the subthalamic nucleus for a patient with drug-resistant focal myoclonic seizure. Annals of Translational Medicine, 2020, 8(1): 18.

12. Di Wang#, Qilin zhou#, Liankun Ren, Yicong Lin, Lehong Gao, Jialin Du, Yuping Wang*. Levetiracetam-induced a new seizure type in a girl with a novel SV2A gene mutation. Clinical Neurology and Neurosurgery, 2019, 181: 64-66.  

13. Yihe Wang#, Yang An#, Xiaotong Fan, Jie Lu, Liankun Ren, Penghu Wei, Bixiao Cui, Jialin Du,  Chao Lu, Di Wang, Huaqiang Zhang, Yongzhi Shan*, Guoguang Zhao*. Comparison between simultaneously acquired arterial spin labeling and 18 F-FDG PET in mesial temporal lobe epilepsy assisted by a PET/MR system and SEEG. Neuroimage Clinical, 2018, 19:824-830.

14. Jia Chen#, Liping Li#, Dongyan Wu, Xiaoxuan Li, Qing Xue, Liying Wang, Jialin Du, Di Wang, Minjing Hu, Liankun Ren*, Yuping Wang. Dynamic Preictal Discharges in Patients With Mesial Temporal Lobe Epilepsy. Journal of Clinical Neurophysiology, 2018:1-7.