王晓飞 教授
医工交叉创新研究院 生物医学工程高精尖中心
北航教师个人主页:http://shi.buaa.edu.cn/wangxiaofei
电子邮箱:xiaofei.wang@buaa.edu.cn
【教育背景】
澳大利亚新南威尔士大学 机械工程 博士 2011年3月 - 2014年12月
大连理工大学 结构工程 硕士 2008年9月 - 2011年7月
中南大学 城市地下空间工程 本科 2004年9月 - 2008年6月
【工作经历】
北京航空航天大学 医工交叉创新研究院 2018年1月-今
新加坡国立大学 生物医学工程系 博士后 2015年2月 - 2018年1月
澳大利亚新南威尔士大学 工程与信息学院 研究助理 2014年11月 - 2015年1月
澳大利亚国立大学 John Curtin医学研究院 访问学者 2014年11月 - 2015年1月
【研究领域】
眼生物力学、医学图像处理、青光眼、高度近视
【代表性科研项目】
1. 北京市自然科学基金,眼调节过程中睫状肌收缩对视乳头变形的影响及其机制研究
2. 国家自然科学基金,太空飞行神经眼综合征的生物力学机制研究
3. 国家级人才青年项目, 眼生物力学
4. 北航“青年拔尖人才计划”, 视乳头生物力学
【代表性论著】
• Wang X, Chang S, Grinband J, Yannuzzi LA, Freund KB, Hoang QV, Girard MJ. Optic nerve tortuosity and
displacements during horizontal eye movements in healthy and highly myopic subjects. British Journal of
Ophthalmology Published Online First: 26 May 2021. doi: 10.1136/bjophthalmol-2021-318968
• Wang X, Tun TA, Nongpiur ME, Htoon HM,Tham YC, Strouthidis NG, Aung T, Cheng CY, Girard M. Peripapillary sclera exhibits a v-shaped configuration that is more pronounced in glaucoma eyes. British Journal of Ophthalmology. 2020;
Published Online First: 17 Dec. 2020. doi:10.1136/bjophthalmol-2020-317900
• Tun TA#, Wang X#, Mani Baskaran, Monisha E Nongpiur, Yih-Chung Tham, Duc Quang Nguyen, Nicholas G Strouthidis, Tin Aung, Ching-Yu Cheng, Michaël JA Girard. Determinants of Lamina Cribrosa Depth in Healthy Asian Eyes: The Singapore
Epidemiology Eye Study. British Journal of Ophthalmology. 2020, doi: 10.1136/bjophthalmol-2020-315840
• Jin Y#, Wang X#, Irnadiastputri S, Mohan R, Aung T, Perera SA, Boote C, Jonas JB, Schmetterer L, & Girard,
MJA. Effect of Changing Heart Rate on the Ocular Pulse and Dynamic Biomechanical Behavior of the Optic
Nerve Head. Investigative ophthalmology & visual science. 2020, 61(4), 27
• Chuangsuwanich T, Pham TH, Wang X, Liang LH, Schmetterer L, Boote C, Girard MJA. Morphometric,
Hemodynamic and Biomechanical Factors influencing Blood Flow and Oxygen Concentration in the
Human Lamina Cribrosa. Investigative ophthalmology & visual science. 2020, in press
• Cheng H, Devalla SK, Pham TH, Zhang L, Tun TA, Wang X, Perera SA, Aung T, Boote C, Thiery A, Michaël
JA Girard. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence
Tomography Images. Translational Vision Science & Technology. 2020, in press
• Zhang L, Beotra MR, Baskaran M, Tun TA, Wang X, Perera SA, Strouthidis NG, Aung T, Boote C, Girard MJA.
In Vivo Measurements of Prelamina and Lamina Cribrosa Biomechanical Properties in Humans. Investigative
ophthalmology & visual science. in press
• Tun TA#, Wang X#, Mani Baskaran, Monisha E Nongpiur, Yih-Chung Tham, Shamira A Perera, Nicholas G Strouthidis, Tin Aung, Ching-Yu Cheng, Michaël JA Girard. Variation of Peripapillary Scleral Shape With Age. Investigative ophthalmology
& visual science. 2019, 60 (10), 3275-3282 (共同一作)
• Devalla SK, Subramanian G, Pham TH, Wang X, Perera S, Tun TA, Aung T, Schmetterer L, Thiéry AH,
Girard MJ. A deep learning approach to denoise optical coherence tomography images of the optic nerve
head. Scientific reports. 2019 Oct 8;9(1):1-3
• Tan NY, Tham YC, Thakku SG, Wang X, Baskaran M, Tan MC, Mari JM, Strouthidis NG, Aung T, Girard MJ,
Cheng CY. Changes in the Anterior Lamina Cribrosa Morphology with Glaucoma Severity. Scientific reports.
2019 Apr 29;9(1):6612.
• Wang, X, Rumpel, H, Baskaran, M, Tun, T, Strouthidis, N, Perera, S, Lim, W, Nongpiur, ME, Lim, W, Aung, T,
Milea, D, Girard, MJA. Optic Nerve Tortuosity and Globe Proptosis in Normal and Glaucoma Subjects. Journal
of Glaucoma, 2019, 28 (8), 691-696
• Hu, L.; Wang, H, Wang, X, Liu, X, Guo, J, Liu, J, Magnetic liquid metals manipulated in the three-dimensional free space. ACS Applied Materials & Interfaces, 2019, 11, 8:8685-8692
• Tan, R.; Wang, X; Chan, Anita S. Y.; Nongpiur, Monisha E.; Boote, Craig; Perera, Shamira; Girard, Michael,
Permeability of the porcine iris stroma, Experimental Eye Research, 2019.02.01, 181: 0~0
• Jin, Y., Wang, X, Zhang, L., Jonas, J. B., Aung, T., Schmetterer, L., & Girard, M. J. Modeling the Origin of
the Ocular Pulse and Its Impact on the Optic Nerve Head. 2018. Investigative ophthalmology & visual science, 59(10), 3997-4010.
• Wang, X, Teoh, C. K. G., Chan, A. S., Thangarajoo, S., Jonas, J. B., & Girard, M. J. Biomechanical Properties
of Bruch's Membrane–Choroid Complex and Their Influence on Optic Nerve Head Biomechanics. 2018. Investigative Ophthalmology
& Visual Science, 59(7), 2808-2817.
• Beotra MR, Wang X, Tun TA, Zhang L, Baskaran M, Aung T, Strouthidis NG, Girard MJA. In Vivo 3-Dimensional Lamina Cribrosa Strains in Healthy, Ocular Hypertensive and Glaucoma Eyes following Acute
Intraocular Pressure Elevation. 2018. Investigative Ophthalmology & Visual Science.
• Wang X, Fisher LK, Milea D, Jonas JB, Girard MJA. Predictions of Optic Nerve Traction Forces and Peripapillary
Tissue Stresses Following Horizontal Eye Movements. Investigative Ophthalmology & Visual Science. 2017.
Vol. 58, 2044-2053
• Wang X, Beotra MR, Zhang L, Girard MJA. In vivo Characterization of Optic Nerve Head Biomechanics for
Improved Glaucoma Management. In: Roberts CJ, Dupps WJ, Downs CD, eds. Biomechanics of the Eye.
Amsterdam, The Netherlands: Kugler Publications; 2018.
• Wang X, Beotra MR, Tun TA, Baskaran M, Perera SA, Aung T, Strouthidis NG, Milea D, Girard MJA. In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye
Movements. Investigative Ophthalmology & Visual Science. 2016. Vol.57, 5825-5833. doi:10.1167/iovs.16-20560 .
• Wang X, Rumpel H, Lim WEH, Baskaran M, Perera SA, Nongpiur ME, Aung T, Milea D, Girard MJA. Finite
Element Analysis Predicts Large Optic Nerve Head Strains During Horizontal Eye Movements. 2016. Investigative
Ophthalmology & Visual Science. Vol.57, 2452-2462. doi:10.1167/iovs.15-18986.
• Wang X, Rumpel H, Lim WEH, Baskaran M, Perera SA, Nongpiur ME, Aung T, Milea D, Girard MJA. Author
Response: Peripapillary Suprachoroidal Cavitation, Parapapillary Gamma Zone and Optic Disc Rotation due to
the Biomechanics of the Optic Nerve Dura Mater. 2016. Investigative Ophthalmology & Visual Science. 2016,
Vol.57, 4374-4375. doi:10.1167/iovs.16-20118
• Wang X, Neely A, McIlwaine G and Lueck C. Biomechanics of Chiasmal Compression: Sensitivity of the
Mechanical Behaviours of Nerve Fibres to Variations in Material Property and Geometry. International Journal
for Computational Methods in Engineering Science & Mechanics. 2016. Vol.17(3): 165-171. doi: 10.1080/15502287.2015.1084069
• Wang X, Neely A, McIlwaine G and Lueck C. Multi-scale analysis of optic chiasmal compression by finite element modelling. Journal of Biomechanics. 47 (10), pp. 2292-2299. doi: 10.1016/j.jbiomech.2014.04.040
• Wang X, Neely A, McIlwaine G, Tahtali M, Lillicrap T and Lueck C. Finite element modelling of optic
chiasmal compression. Journal of Neuro-Ophthalmology. 34(4): 324-30. doi: 10.1097/WNO.0000000000000145
• Jain N, Jain S, Wang X, Neely A, Tahtali M, Jain S and Lueck C. Visualization of Nerve Fiber Orientations
in the Human Optic Chiasm Using Photomicrographic Image Analysis. Investigative Ophthalmology & Visual
Science. 2015, Vol.56 (11), 6734-6739. doi:10.1167/iovs.15-17443
• Lillicrap T, Tahtali M, Neely A, Wang X, Bivard A, and Lueck C. A Model Based on the Pennes Bioheat
Transfer Equation is Valid in Normal Brain Tissue but not Brain Tissue Suffering Focal Ischaemia. Australian
Physical & Engineering Sciences in Medicine. 2017.