郝飞 讲师 硕士生导师
医学科学与工程学院
电子邮箱：haofei@buaa.edu.cn
【教育背景】
2013.09-2017.06，首都医科大学，基础医学院，博士
2006.09-2013.06，大连医科大学，七年制临床医学，学士、硕士
【工作经历】
2021.11-至今，北航医学科学与工程学院，讲师
2017.07-2021.10，北航生物与医学工程学院，博士后
2017.01-2017.06，美国纽约州立大学上州医学院，访问学者
【研究领域】
1. 医用生物活性材料
2.神经系统损伤与修复
3.神经退行性疾病
【代表性科研项目】
1. 国家自然科学基金青年项目，82201542，NT3-壳聚糖生物活性材料修复成年脊髓损伤的神经环路机理研究，2023.01-2025.12，30万元，主持
2. 北京市自然科学基金青年项目，7214301，NT3-壳聚糖生物活性支架激活内源性神经发生修复成年脊髓损伤的机制研究，2021.01-2022.12，10万元，主持
3. 中国博士后科学基金面上项目，2018M641145，活性生物材料支架促进脊髓损伤大鼠膀胱环路重建的研究，2019.01-2019.12，5万元，主持
4. 北京航空航天大学医工卓越创新计划，JKF-YG-22-B001，bFGF-壳聚糖生物活性材料调控内源性神经发生和血管发生修复成年缺血性脑卒中的研究，2022.07-2022.12，7万元，主持
5. 国家自然科学基金面上项目，31970970，脊髓损伤及促神经再生治疗对脑功能网络调节机制研究，2020.01-2023.12，58万元，参与
6. 北京市自然科学基金青年项目，7194286，陈旧性脊髓损伤胶质瘢痕的MRI多特征分析与精准鉴别研究，2019.01-2020.12，10万元，参与
【代表性论著】
1. Fei Hao, Fan Jia, Peng Hao, Hongmei Duan, Zijue Wang, Yubo Fan, Wen Zhao, Yudan Gao, Orion R. Fan, Fuqiang Xu, Zhaoyang Yang, Yi E. Sun, Xiaoguang Li. Proper wiring of newborn neurons to control bladder function after complete spinal cord injury. Biomaterials (IF=15.304, Q1). 2023;292:121919.
2. Xiao Liu#, Fei Hao#, Peng Hao, Jingxue Zhang, Liqiang Wang, Si-Wei You, Ningli Wang, Zhaoyang Yang, Kwok-Fai So, Xiaoguang Li. Regeneration and functional recovery of the completely transected optic nerve in adult rats by CNTF-chitosan. Signal Transduction and Targeted Therapy (IF=38.104, Q1). 2023;8 (1):81.
3. Fei Hao, Chun Yang, Sha-Sha Chen, Yan-Yan Wang, Wei Zhou, Qiang Hao, Tao Lu, Barry Hoffer, Li-Ru Zhao, Wei-Ming Duan, Qun-Yuan Xu. Long-term protective effects of AAV9-mesencephalic astrocyte-derived neurotrophic factor gene transfer in parkinsonian rats. Experimental Neurology (IF=5.62, Q2). 2017;291:120-133.
4. Fei Hao, Aiping Li, Huan Yu, Meichen Liu, Yachen Wang, Jing Liu, Zhanhua Liang. Enhanced neuroprotective effects of combination therapy with bone marrow-derived mesenchymal stem cells and Ginkgo Biloba extract (EGb761) in a rat model of experimental autoimmune encephalomyelitis. Neuroimmunomodulation. 2016;23:41-57.
5. Fei Hao, Nan-Nan Zhang, Dong-Mei Zhang, Huan Yu, Cong-Shu Xiao, Ai-Ping Li. Chemokine fractalkine attenuates overactivation and apoptosis of BV-2 microglial cells induced by Extracelluar ATP. Neurochemistry Research. 2013;38:1002-1012.
6. Zijue Wang, Hongmei Duan, Fei Hao, Peng Hao, Wen Zhao, Yudan Gao, Yiming Gu, Jianren Song, Xiaoguang Li, Zhaoyang Yang. Circuit reconstruction of newborn neurons after spinal cord injury in adult rats via an NT3-chitosan scaffold. Progress in Neurobiology (IF=10.885, Q1). 2023;220:102375.
7. Peng Hao, Hongmei Duan, Fei Hao, Lan Chen, Min Sun, Kevin S Fan, Yi Eve Sun, David Williams, Zhaoyang Yang, Xiaoguang Li. Neural repair by NT3-chitosan via enhancement of endogenous neurogenesis after adult focal aspiration brain injury. Biomaterials (IF=15.304, Q1). 2017;140:88-102.
8. Wenxi Lian, Fei Hao, Peng Hao, Wen Zhao, Yudan Gao, Jia-Sheng Rao, Hongmei Duan, Zhaoyang Yang and Xiaoguang Li. Distribution Heterogeneity of Muscle Spindles Across Skeletal Muscles of Lower Extremities in C57BL/6 Mice. Frontiers In Neuroanatomy. 2022;16:838951.
9. Hao Fan, Hongmei Duan, Peng Hao, Yudan Gao, Wen Zhao, Fei Hao, Xiaoguang Li, Zhaoyang Yang. Cellular regeneration treatments for traumatic brain injury. Medicine in Novel Technology and Devices. 2022;16:100182.
10. Fa Dong Liu, Hong Mei Duan, Fei Hao, Wen Zhao, Yu Dan Gao, Peng Hao, Zhao Yang Yang, Xiao Guang Li. Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats. Neural Regeneration Research. 2022;17(5): 1146-1155.
11. Fadong Liu, Fei Hao, Peng Hao, Hongmei Duan, Wen Zhao, Yudan Gao, Zhaoyang Yang, Xiaoguang Li. bFGF-chitosan scaffolds effectively repair 20 mm sciatic nerve defects in adult rats. Biomedical Materials. 2021;16(2):025011.
12. Chun Yang, Fei Hao, Jun He, Ronald L. Klein, Tao Lu, Li-Ru Zhao,Wei-Ming Duan. Sequential AAV9-green fluorescent protein gene transfer causes massive inflammatory and immune responses in rat striatum. Human Gene Therapy. 2016;27:528-543.
13. Chen Li, Yong-Xin Zhang, Chun Yang, Fei Hao, Sha-Sha Chen, Qiang Hao, Tao Lu, Ting-Yu Qu, Li-Ru Zhao, Wei-Ming Duan. Intraventricular administration of endoneuraminidase-N facilitates ectopic migration of subventricular zone-derived neural progenitor cells into 6-OHDA lesioned striatum of mice. Experimental Neurology. 2016;277:139-149.
14. Sha-Sha Chen, Chun Yang, Fei Hao, Chen Li, Tao Lu, Li-Ru Zhao, Wei-Ming Duan. Intrastriatal GDNF gene transfer by inducible lentivirus vectors protects dopaminergic neurons in a rat model of parkinsonism. Experimental Neurology. 2014;261:87-94.
【招生】
欢迎具有生物学、医学、生物材料等相关专业背景的优秀学子加入，欢迎对神经科学感兴趣的优秀学子加入，有意者可直接发送简历至邮箱：haofei@buaa.edu.cn。
